Dra. Luz María Del Razo Jiménez

e-mail: ldelrazo@cinvestav.mx
Teléfono: +52 55 5747-3306
Fax: +52 55 5747-3395

Investigador Cinvestav 3E

Laboratorio de Contaminantes Inorgánicos

  • Doctora en Ciencias en Toxicología, 1997, CINVESTAV-IPN. México, D.F.
  • Estancia posdoctoral: Agencia de Protección del Ambiente de EUA y la Universidad de Carolina del Norte, 1997-1999, Chapell Hill, EUA.
  • Investigador Nacional Nivel III

Líneas de Investigación:

  • Toxicidad y toxicocinética de arsénico y fluoruro.
  • Sistemas reguladores de homeostasis intracelular.
  • Biomarcadores metabólicos y bioquímicos de exposición y efecto por exposición a arsénico y fluoruro.
  • Evaluación de los mecanismos involucrados en la patogénesis de enfermedades crónico-degenerativas en respuesta a contaminantes ambientales inorgánicos.
     
ArtículosEstudiantesDonativos y Distinciones

Jiménez-Córdova M.I., González-Horta C., Ayllón-Vergara J.C., Arreola-Mendoza L., Aguilar-Madrid G., Villareal-Vega E.E., Barrera-Hernández A., Barbier OC, Del Razo L.M. Evaluation of vascular and kidney injury biomarkers in Mexican children exposed to inorganic fluoride. Environmental Research, 169:220-228 (2019).

Jiménez-Córdova M. I., Cardenas-Gonzalez M., Aguilar-Madrid G., Sanchez-Peña L. C., Barrera-Hernández A., Domínguez-Guerrero I. A., González-Horta C., Barbier O. C., Del Razo L M. Evaluation of kidney injury biomarkers in an adult Mexican population environmentally exposed to fluoride and low arsenic levels. Toxicology and Applied Pharmacology, 352:97-106 (2018).

Osorio-Yáñez C., Ayllon-Vergara J. C., Arreola-Mendoza L., Aguilar-Madrid G., Hernández-Castellanos E., Sánchez-Peña L. C., Del Razo L. M. Blood Pressure, Left Ventricular Geometry, and Systolic Function in Children Exposed to Inorganic Arsenic. Environ Health Persp 123: 629-635 (2015).

Esquivel-Gaón  M., Anguissola S., Garry D., Gallegos-Melgar A., Muñoz-Saldaña J., Dawson K.A., De Vizcaya-Ruiz A., Del Razo L. M. Bismuth-based nanoparticles as the environmentally – friendly replacement for lead-based piezoelectrics. RSC Advances 5, 27295 (2015). 

Osorio-Yáñez C, Ayllon-Vergara JC, Aguilar-Madrid G, Arreola-Mendoza L, Hernández-Castellanos E, Barrera-Hernández A, De Vizcaya-Ruíz A, Del Razo LM. Carotid Intima-Media Thickness and Plasma Asymmetric Dimethylarginine in Mexican Children Exposed to Inorganic Arsenic. Environ Health Persp 121: 1090-1096 (2013).

Barbier O., Arreola-Mendoza L., Del Razo LM. Molecular Mechanisms of Fluoride Toxicity Chemico-Biological Interactions, 188:319-333 (2010).

Del Razo LM, García-Vargas GG, Valenzuela OL, Hernández Castellanos E, Sánchez Peña LC, Currier JM, Drobná Z, Loomis D, Stýblo M. Exposure to arsenic in drinking wáter is associated with increased prevalence of diabetes: a cross-sectional study in the Zimapán and Lagunera regions in Mexico Environmental Health, 10:73.

Garcia Montalvo, E.A, Reyes-Pérez H., Del Razo LM Fluoride Exposure Impairs Glucose Tolerance via Decreased Insulin Expression and Oxidative Stress Toxicology, 263: 75-83, (2009).

Valenzuela O.L, Drobná Z., Hernández.-Castellanos E., Sánchez- Peña L.C., García-Vargas GG, Borja-Aburto V.H., Stýblo M., Del Razo LM. Association of AS3MT Polymorphisms and the Risk of premalignant Arsenic Skin Lesions Toxicology and Applied Pharmacology, 239: 200-207, (2009).

Valenzuela O.L., Germolec D.R., Borja-Aburto V.H., Contreras-Ruiz J.,Garcia-Vargas G.G, Del Razo LM. Chronic arsenic exposure increases TGFalpha concentration in bladder urothelial cells of Mexican populations environmentally exposed to inorganic arsenic Toxicol. Appl Pharmacol. 222: 264-270 (2007).

García-Chávez E., Jiménez I., Segura B., Del Razo LM. Lipid oxidative damage and distribution of inorganic arsenic and its metabolites in rat nervous system after arsenite exposure: Influence of alpha tocopherol supplementation. NeuroToxicology 27:1024-1031 (2006).

Izquierdo-Vega, J.A., Soto, C.A., Sanchez-Peña, L.C., De Vizcaya- Ruiz, A., Del Razo LM. Diabetogenic effects and pancreatic oxidative damage in rats subchronically exposed to arsenic. Toxicology Letters. 160:135-142 (2006)
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Valenzuela, O.L., Borja-Aburto, V.H., Garcia-Vargas G.G, Cruz-Gonzalez M.B.,Garcia-Montalvo-E.A., Calderon-Aranda, E.S., Del Razo LM. “Urinary Trivalent Methylated Arsenic Species in a Population Chronically Exposed to Inorganic Arsenic”. Environ Health Persp, 113:250-254 (2005)
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